10 issues it is best to find out about Main Applewhite


It is official. The College of Houston named its new head soccer coach, they usually did not need to look very far for him.

After two seasons because the offensive coordinator for UH, former College of Texas quarterback Main Applewhite has landed his first head teaching gig.

SEE ALSO: UH pronounces new head soccer coach

Listed here are 10 issues it is best to find out about Htowntakeover’s new head coach:

1. Applewhite is a local of Baton Rouge, La.

2. He was a beginning quarterback for Catholic Excessive Faculty the place he threw for 50 touchdowns in additional than two years.

three. Applewhite has thirteen years of teaching expertise.

four. He was the all-time chief in passing yards, passing touchdowns, passing makes an attempt and complete offense at College of Texas.

5. Applewhite was 22-eight document as beginning quarterback for UT.

6. He graduated from the College of Texas with a level in sports activities administration.

7. Applewhite signed with the New England Patriots days after the 2002 draft, however give up previous to the beginning of camp to complete his diploma and pursue a profession in teaching.

eight. He served as offensive coordinator at Rice College in 2006, and on the College of Alabama beneath Nick Saban in 2007. He was the youngest offensive coordinator amongst Division I-A faculties at the moment.

9. Applewhite is married with two youngsters – one daughter, one son.

10. He served as UH offensive coordinator for 2 seasons.

(Copyright ©2016 KTRK-TV. All Rights Reserved.)

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Main Alzheimer's researcher joins Sanford Burnham Prebys

A prime mind researcher has joined Sanford Burnham Prebys Medical Discovery Institute, bringing with him groundbreaking work on the genetics of Alzheimer’s illness and a workforce of 25 researchers.

Dr. Jerold Chun will begin at Sanford Burnham Prebys on Dec. 15. He comes from The Scripps Analysis Institute, the place he has been a professor since 2003. Chun can be professor and senior vice chairman of SBP’s neuroscience drug discovery operations.

Chun focuses on mosaicism, the genetic variations in cells within the physique, as soon as assumed to be principally genetically equivalent. A 2015 research led by Chun discovered that neurons in brains of Alzheimer’s sufferers had considerably extra genetic variation than regular brains, together with additional copies of a gene linked to the illness.

The rent is a coup for SBP, stated Dr. Paul Aisen, one other Alzheimer’s skilled in San Diego.

“He’s an incredible primary neuroscientist who’s had monumental discoveries which might be advancing the sector,” stated Aisen, who heads the College of Southern California’s Alzheimer’s Therapeutic Analysis Institute in San Diego.

“I feel the genetic mosaicism that he has uncovered could be very fascinating and probably essential for our understanding of illness and the event of remedies,” Aisen stated. He was interviewed on the Medical Trials for Alzheimer’s Illness convention in downtown San Diego, which he helped arrange.

Mary Ball, president and CEO of Alzheimer’s San Diego, stated Chun will be capable of give widespread help for creating medicine for Alzheimer’s.

“I feel Jerold goes to have the ability to additional his analysis, and he’s going to have the ability to additional different individuals’s analysis right into a drug,” Ball stated.

No drug available on the market impacts the illness’s underlying course, at greatest, medicine might briefly sluggish the psychological deterioration that’s a illness hallmark.

Somebody of Chun’s stature might have gone nearly anyplace, she stated, and it’s to San Diego’s credit score as an Alzheimer’s analysis middle that he stayed right here.

Conversely, Chun’s departure takes a luminous biomedical star away from The Scripps Analysis Institute. It has a couple of different notable losses in recent times, such because the 2012 recruitment of star chemist Okay.C. Nicolaou by Rice University in Houston, and 2011’s loss of Nobel laureate Bruce Beutler to UT Southwestern Medical Center in Dallas.

Beutler’s loss was especially poignant because he is the son of Ernest Beutler, a noted TSRI hematologist. The elder Beutler died in 2008 — not surviving to see his son share the 2011 Nobel Prize in Physiology or Medicine.

However, Scripps retains two Nobelists, Kurt Wüthrich and K. Barry Sharpless, and others considered to be potential winners, including TSRI President Peter Schultz. Other stars include chemist Phil Baran, chemical biologist Floyd Romesberg and structural biologist Erica Ollmann Saphire.

TSRI praised Chun’s contributions.

“Jerold Chun’s work at TSRI has helped to characterize the basis for a number of neurodegenerative diseases — and to develop potential treatments,” said James Williamson, TSRI’s dean of graduate and postdoctoral studies and vice president for academic affairs.

“TSRI is proud of its ability to attract talented faculty and best-in-class researchers, like Dr. Chun. It is no surprise to us that other institutions would want to recruit from our ranks,” Williamson said.

“As part of our commitment to renewing faculty on an ongoing basis, we recently initiated a bicoastal search for two new faculty members, and we are actively recruiting for a junior faculty member in La Jolla – this is a high priority for the Institute.”

New challenge

Chun said he has enjoyed working at TSRI, a global powerhouse in basic scientific research. However, he was drawn by SBP’s emphasis on translating research findings into clinical treatments.

Chun said he got received a “significant” budget from SBP, enough to support his team of 25 scientists, but declined to give a dollar amount.

In addition, Chun, 57, said he had reached an age where he wanted to move to a different stage of his scientific career. With their last child to leave home for college, Chun and his wife are now “empty nesters,” looking for new opportunities.

SBP had been interested in Chun for some time, he said. He had been contacted by a “headhunter” for an unidentified biomedical institute, and as his usual practice, didn’t respond.

Then this summer, Chun attended a meeting on Alzheimer’s in the office of Kevin Faulconer, San Diego’s mayor.

“I ran into Perry Nisen, the CEO of Sanford Burnham,” Chun said. “We started chatting, and realized that yes, that headhunter had been sent out by him. So we began some informal discussions, and one thing led to another. It made sense to make this move.”

“One of the key items was the opportunity to really help to guide some of the therapeutic problems for neuroscience-related drug discovery,” he said.

“Perry Nisen, of course, came from (major drug company) GlaxoSmithKline. His vision is to ramp up the research process to translate discoveries, and I’m 100 percent of that same view.”

SBP welcomed Chun in a statement.

“He brings a distinguished academic record and proven ability to lead world-class neuroscience drug discovery efforts to our Institute,” Dr. Kristiina Vuori, president of SBP, said in the statement.

“We look forward to supporting and working with Dr. Chun on his quest to create innovative solutions for the many unmet needs of patients with neurological disorders.”

Many roles

Chun’s research has revealed a number of roles for genetic mosaicism, not only in disease but in health.

The 2015 study found that Alzheimer’s patients have brains with significantly more copies of fragments from chromosome 21. The fragments carry the gene for APP, or amyloid precursor protein, which has been linked to Alzheimer’s.

This discovery also sheds light on the condition of those with Down syndrome, which causes mild to severe mental retardation and health problems of varying severity. Those with Down syndrome carry an extra copy of chromosome 21, or part of one. Nearly all develop Alzheimer’s if they live long enough.

The discoveries started in 2001, when Chun reported that developing brain cells normally produce different genomes via aneuploidy – the gain and/or loss of chromosomes.

In 2005 Chun and colleagues reported that normal human brains exhibit chromosome 21 mosaicism, containing both more and fewer than the normal two copies. About 4 percent of aneuploid brain cells had 1 or 3 copies of the chromosome, a smaller number had four copies.

In 2010 Chun and colleagues reported finding an even more widespread change in the genome of brain cells they dubbed “DNA content variation” or DCV.

Besides Alzheimer’s, Chun’s work has implications for other neurological diseases, including Parkinson’s, multiple sclerosis, and depression. 

Chun received his M.D. and Ph.D. degrees at Stanford University. He then worked as a postdoctoral fellow at MIT’s Whitehead Institute under National Medal of Science winner Rudolf Jaenisch and David Baltimore, a Nobel Prize winner.


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‘What number of of you killed a negro?’: Charleston NAACP says cops see shootings as ‘badge of honor’

CHARLESTON — Dot S. Scott, the president of the Charleston chapter of the NAACP, stated this week that the black group in her metropolis was at a breaking level because of the current mistrial of a former police officer who was seen on video capturing Walter Scott within the again, and due to the continued federal trial of Dylann Roof, who admitted killing 9 members of Emanuel AME Church.

Uncooked Story sat down with Scott on Tuesday to speak about how the group was coping with the information that a jury had refused to convict former North Charleston police officer Michael Slager for the homicide of Walter Scott.

“The trial that ended final week with a hung jury was disappointing,” Scott admitted. “I feel we fared properly when it comes to not having any violence or issues like that. That was considered one of my considerations as a result of there shouldn’t have been a purpose to not have been capable of convict him. The video that they had as proof, it’s exhausting to elucidate away that any individual sane and truthful might watch it as a juror and say, ‘I simply can’t convict him.’”

“We’ve got come to anticipate so little when it comes to equity within the justice system,” she remarked. “As a result of the bar is about so low, the expectations are so low. We’ve seen it, we’ve had video tapes earlier than — that was in all probability a part of why you continue to don’t have the violent blow up but.”

“However but, I really feel like we’re on the precipice of one thing occurring, that one subsequent factor. What’s going to be the one factor that we’re going to lose all this peace and Kumbaya.”

Scott stated that, so typically, officers defend the killing of black males by claiming that they have been in worry for his or her lives.

“Why are you a police officer if the sight of a black man causes you to worry on your like?” she requested. “Did race have something to do with it? Hell sure. I don’t assume that officer would have shot one other citizen of one other shade within the again like that.”

“Whenever you watch him, it was cool, calm like he was doing goal follow,” Scott stated of Officer Slager. “Clearly [Walter Scott] doesn’t have a weapon or something, he’s no hazard to you or anyone else operating away. ‘No, we acquired to kill him.’ He in all probability stated, ‘Negro, I’m not operating behind you, I’m simply not doing it.’”

Scott lamented that there had been so many shootings in North Charleston that it had develop into a “badge of honor” for an officer to kill a black man.

“It was virtually like a badge of honor, ‘Let me simply shoot one in every of these black guys,’ and ‘What number of of you’ve killed a negro?’ or one thing like that. As a result of we don’t shoot canine down like that. We’ll attempt to not kill an animal faster than we might attempt to not kill a black man. It’s what it’s.”

In accordance the NAACP chief, the Dylann Roof trial is “exhausting to swallow” as a result of it was forcing the black group to relive the trauma of the 2015 mass capturing at Emanuel AME Church.

“[The defense attorneys are] not making an attempt to say Dylann Roof didn’t do it, you might have none of that,” she defined. “However I feel the most important worry for the system right here is that they don’t need Dylann Roof to be his symbolize himself [in court] as a result of Dylann goes to place a mirror in entrance of them and say, ‘You realize what. I did this as a result of I meant to and I’m not a lot of an remoted case.’”

Scott additionally identified that systemic racism might by no means actually be addressed till individuals of all colours — notably whites — stood up and took public actions.

“It doesn’t assist lots to empathize and sympathize with me behind closed doorways,” Scott stated. “It helps extra for white people to start to say sufficient is sufficient and it’s incorrect. However these are individuals you go to church with, the are individuals we golf with, these are my enterprise companion — so we don’t say something. So, it’s virtually like we sanction that it’s alright to try this.”

“It’s going to take extra — identical to all of the lynching that was happening and why the NAACP got here to be since you had these white Jews and folk who have been a part of the system that began the NAACP with folks. If we don’t do this — and I can see that extra people are reaching out making an attempt to try this — but when we don’t do this, we’re not going to maneuver ahead in any approach.”

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Gov't proposal envisions telephone calls on airline flights


Airways might let passengers make in-flight telephone calls utilizing Wi-Fi beneath a proposal from federal regulators.

Flight attendants and others have complained that the calls could possibly be disruptive. However the Division of Transportation stated Thursday that it envisioned permitting the calls if airways inform all clients concerning the coverage once they purchase their tickets.

That approach, clients might make different journey preparations in the event that they feared sitting subsequent to passengers chatting on their telephones.

There’s a 60-day remark interval, and the proposal leaves the door open to the likelihood that federal officers might nonetheless impose an outright ban.

The Federal Communications Fee prohibits passengers from making cellphone calls throughout flights, however not Wi-Fi calls.

“At the moment’s proposal will be sure that air vacationers aren’t unwillingly uncovered to voice calls, as lots of them are troubled over the thought of passengers speaking on cell telephones in flight,” Transportation Secretary Anthony Foxx stated in a press release. In 2014, the division issued a request for public feedback on the potential for allowing the calls and the response was overwhelmingly destructive.

Sara Nelson, president of the Affiliation of Flight Attendants-CWA, stated something in need of a ban on calls is “reckless.” Flight attendants have stated beforehand that they worry the calls might result in fights between passengers who need to make calls and passengers who do not need to take heed to the conversations.

“It threatens aviation safety and will increase the probability of battle within the skies. It threatens security for crews and passengers,” Nelson stated.

Nevertheless, the U.S. airways’ commerce group opposes a authorities ban on in-flight calls.

“We now have lengthy held that this was not a matter for DOT to manage, and we consider airways ought to be capable of decide what providers could be safely provided in flight and make these selections based mostly on what’s in the most effective pursuits of their passengers and crewmembers,” a spokeswoman for Airways for America, Kathy Grannis Allen, stated by e-mail.

Southwest Airways and Alaska Airways stated they haven’t any plans to permit voice calls.

“Our clients have expressed considerations relating to the doubtless disruptive nature of in-flight voice calls,” stated Southwest spokesman Brian Parrish. Alaska Airways spokeswoman Bobbie Egan stated the service surveyed passengers a couple of years in the past and received “a robust response” that they did not need calls.

A Delta Air Strains spokeswoman famous that the service has opposed voice requires a number of years.

United Airways stated it was reviewing the proposal and would take heed to the views of consumers and staff. American referred inquiries to the commerce group. JetBlue didn’t have an instantaneous remark.


Koenig reported from Dallas.

(Copyright ©2016 by The Related Press. All Rights Reserved.)

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Lady finds stranger in bathe


SCOTTSDALE, AZ (KRON)- Police arrested a person in nothing however a towel after breaking into a lady’s residence.

The lady hid together with her daughters in a bed room and referred to as 9-1-1.

50 yr-previous Scott Alan Lamarsh kicked his method inside the house the place a lady and her two daughters have been sleeping upstairs.

“His garments have been scattered throughout my home. He was in my main bedroom whereas I used to be sleeping. And I didn’t hear something till he began screaming in my toilet,” says the lady.

The cops had been with Lamarsh earlier that night time and in response to courtroom paperwork he was drunk and received right into a battle. Police gave him a courtesy journey residence however drove away earlier than he went inside.

They later came upon that the person lived on the home a number of years in the past. Officers apologized to her after the accident and she or he hopes one thing like this by no means occurs to anybody else.

CNN newssource contributed to this report

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With shutdown looming, Senate chief Mitch McConnell urges passage of finances

With the specter of a partial authorities shutdown hours away, Senate Majority Chief Mitch McConnell Friday urged the Senate to move a stopgap price range, saying, “It’s time to get critical right here.”

The Senate is mired in an issue over a plan that retains a lot of the authorities operating via April 28.

A key sticking level: Well being-care advantages for hundreds of retired coal miners which are set to lapse on Dec. 31. Republican leaders included a 4-month extension of the advantages within the greater spending invoice, however that’s run into opposition from some coal-state Democrats.

The Home handed the invoice Thursday. But when the Senate doesn’t, elements of the federal government will start shutting down after midnight.

It’s unlikely, although, that any shutdown would go into the work week subsequent yr. For procedural causes, the matter is nearly sure to be resolved by Sunday night time.

The invoice would prolong the advantages for some sixteen,000 retired miners by way of the top of April. Sen. Joe Manchin, D-W.Va., and his allies need a one-yr extension. An extended-time period repair for the United Mine Staff of America pension and well being care fund that they had sought seems to be off the desk for now.

Even a one-yr extension shall be robust to get, because the Home has left for the yr.

McConnell was assured the retirees wouldn’t lose advantages subsequent yr, together with greater than three,000 in his residence state of Kentucky.

“I feel it’s extremely unlikely that we’ll take it away,” he stated. “It’s been my intention that the miner advantages not expire on the finish of April subsequent yr.”

And, he pledged, “I’m going to work with my colleagues to stop that.”

So cross the finances, he urged. It a minimum of ensures well being look after miners by way of April. “Failure to move it ensures it goes away on the finish of the month,” McConnell stated.

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Lady charged after allegedly stealing UPS packages off NW Harris Co. doorstep


A lady is charged with theft after authorities say she stole UPS packages crammed with Christmas presents from a resident’s doorstep on Sunday in northwest Harris County.

The Precinct four Constable’s Workplace says a neighbor within the 12900 block of Wincrest Courtroom referred to as authorities and stated a lady stole the packages and fled, however the witness managed to get a car description a partial license plate quantity.

Deputies searched the world and located the automotive matching the witness’ description simply outdoors the neighborhood. The witness recognized the driving force because the alleged thief, based on authorities.

Jessica L. Jordan is now charged with misdemeanor theft.

Precinct four says the packages — which contained toys for the sufferer’s grandchildren — made it again to the rightful proprietor.

(Copyright ©2016 KTRK-TV. All Rights Reserved.)

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Blind surfer goals for the right wave

For many surfers, it’s exhausting sufficient discovering that good mixture of board, seashore, stability and brute power to battle the waves. Now think about doing it with no eyes or legs. 

At present by way of Sunday, seventy seven disabled athletes from 21 nations will face that problem on the 2016 Stance ISA World Adaptive Browsing Championship at La Jolla Shores. Among the many rivals is native surfer Scott Leason, who misplaced his sight to a robber’s bullet 23 years in the past.

On Wednesday, the 60-yr-previous Metropolis Heights man was training his strikes on the Shores and his distinctive browsing fashion drew a small however fascinated crowd of onlookers.

For greater than 50 years, the ISA has organized, ruled and promoted worldwide browsing competitions. This yr, the ISA was profitable in getting browsing acknowledged as an official Olympic sport (starting with the Tokyo Olympics in 2020). Aguerre stated his subsequent aim is to get adaptive browsing acknowledged by the Paralympic Video games, hopefully for 2020 or 2024. A Paralympics official will probably be on-hand to watch this weekend’s competitors.

As a result of extra skilled athletes with differing talents are competing this yr, Aguerre stated two new divisions have been added. One is for visually impaired athletes like Leason. The opposite is for surfers who experience standing on their boards (versus laying on the board or driving in a kneeling place). San Diego resident Danielle “Dani” Burt, who misplaced her proper leg in a 2004 motorbike accident on Palomar Mountain, is among the many surfers who will compete within the new standing division. Burt, who works as a bodily therapist at Sharp Memorial Hospital, was just lately topped the 2016 U.S. Adaptive Browsing Champion within the standing, degree 2, class.

On the inaugural championship in La Jolla in September 2015, Leason was considered one of solely two blind surfers within the contest. This yr he’ll face seven others from all over the world.

“I’m nervous as hell,” he stated. “I really feel the strain of representing the U.S. as the primary blind browsing champion, however it’s additionally an honor and a privilege.”


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